Ginger
Zingiber officinale
Ginger is the rhizome of Zingiber officinale, and in supplement form it is used mainly for nausea and digestive discomfort rather than for the liver.
AlphaCleanse, 2-capsule serving
- Milk Thistle165 mg
- Spirulina110 mg
- Ginger110 mg
- Turmeric110 mg
- Dandelion Root55 mg
- Reishi MushroomReishi55 mg
- Beetroot55 mg
- Burdock Root27.5 mg
- Rhubarb Root27.5 mg
- Schisandra BerrySchisandra27.5 mg
- Nettle Leaf27.5 mg
- BioPerine2.75 mg
Every amount is printed on the label. No proprietary blend.
That distinction matters on a liver-supplement page, so it is worth making early.
Ginger's best human evidence is about the stomach, not the liver, and the liver findings that exist come from a dose far above ours.
AlphaCleanse contains 110 mg, and the reason it is in the formula is the digestive half of what people come to us for: bloating and post-meal discomfort.
This page also settles something the category usually leaves hanging.
The warning that ginger thins your blood has been tested in people rather than assumed. A randomised crossover in 12 healthy men found that 7 days of ginger at recommended doses changed nothing about INR, platelet aggregation or warfarin clearance.
That is a straighter answer than most liver supplements can give you about their own ingredients.
How much is in AlphaCleanse
In short: AlphaCleanse contains 110 mg of ginger per 2-capsule serving, joint second by weight on its 12-ingredient panel.
110 mg of ginger per 2-capsule serving. That is joint second by weight on the AlphaCleanse Supplement Facts panel, level with turmeric and spirulina.
It sits behind milk thistle at 165 mg and ahead of the 55 mg and 27.5 mg ingredients below it.
The panel lists ginger, not a standardised gingerol extract, and does not state a gingerol percentage.
There is no proprietary blend. All 12 ingredients carry their own milligram amount, and AlphaCleanse is made with organic ingredients.
What the evidence shows
In short: ginger's strongest human evidence is nausea rather than the liver, and the fatty liver trial used 2 g a day.
For digestion, the human evidence is real and it is about nausea.
A systematic review and meta-analysis pooled 14 randomised trials in 1,506 surgical patients and found ginger reduced postoperative nausea scores against placebo at 2, 6 and 12 hours after surgery, with standardised mean differences of -1.10, -1.54 and -2.04 respectively.
It did not reduce the incidence of vomiting or the use of rescue antiemetics (Lu et al., International Journal of Nursing Studies 2022;125:104094, PMID 34700257).
NCCIH's summary is narrower still: ginger "may be helpful for nausea and vomiting associated with pregnancy", while "most studies of ginger for motion sickness haven't shown it to be helpful" (NCCIH).
For the liver there is one small randomised trial worth citing. What it tested:
- 44 adults with fatty liver, taking 2 g a day of ginger supplement or matched placebo for 12 weeks.
- Both arms also followed a modified diet and activity programme.
- ALT, gamma-glutamyl transferase, inflammatory cytokines, the insulin resistance index and hepatic steatosis grade all fell against placebo.
- AST and fibrosis did not change (Rahimlou et al., Hepatitis Monthly 2016;16(1):e34897, PMID 27110262).
44 people, 12 weeks, and a diet intervention running in both arms is a pilot, and the authors call it one.
Where our dose sits: well below. That trial used 2 g a day; AlphaCleanse contains 110 mg, roughly a 1 to 18 ratio.
LiverTox puts the typical supplement dose at up to the equivalent of 1,000 mg of dried powdered extract daily, which our serving is also under.
Both of those comparisons are only possible because the amount is printed: 110 mg, on the panel, alongside the other 11.
Why this dose
In short: 110 mg of ginger is here for the digestive side of the formula rather than as a liver active.
One ingredient in AlphaCleanse carries the clinical weight, and it is not this one.
Milk thistle sits at 165 mg as the anchor, and the other 11, ginger at 110 mg among them, are in for breadth, every amount printed on the panel where anyone can check it.
Holding 110 mg of ginger against a 2 g solo trial is the wrong measurement, because ginger was never put in here as a solo botanical.
The formulation logic is specific.
AlphaCleanse's registered study measured abdominal bloating, abdominal pain and nausea as secondary outcomes alongside the blood panel, because those are the symptoms that bring people to a liver supplement in the first place.
Ginger is on the panel for that side of the formula, and the digestive evidence for ginger is stronger than the hepatic evidence at any dose.
Our own 12-week study in 40 adults recorded a 38.6% fall in digestive symptom score.
It was single-arm and open-label with no placebo group, so it cannot say how much of that belongs to ginger rather than to the other 11 ingredients, and we present it as a whole-formula number because that is what it is.
If you want to know what each of the 12 ingredients is doing and at what amount, the panel prints all of it, which is the check a proprietary blend does not let you run.
Safety and interactions
In short: LiverTox scores ginger E, the likeliest side effect is heartburn, and the human warfarin test found no change.
The NIH's LiverTox database gives ginger a likelihood score of E, unlikely cause of clinically apparent liver injury, and reports no hepatotoxicity across more than 100 clinical trials.
A single Japanese case report involved a multi-ingredient botanical product whose purity was never verified (LiverTox, NBK600585).
Side effects. NCCIH lists abdominal discomfort, heartburn, diarrhoea, and mouth or throat irritation.
Reflux is the one our own reviewers are most likely to notice, and taking the capsules with food rather than on an empty stomach is the usual fix.
Blood thinners. Ginger appears on antiplatelet caution lists, and the best human test does not support the warning at supplement doses.
In an open-label 3-way crossover, 12 healthy men took a single 25 mg dose of warfarin alone and after 7 days of pretreatment with ginger at recommended doses. What was measured, and unchanged:
- INR.
- Platelet aggregation.
- Warfarin enantiomer clearance.
- CYP2C9 activity (Jiang et al., British Journal of Clinical Pharmacology 2005;59(4):425-432, PMID 15801937).
12 healthy young men is not the same population as a 60 year old on long-term warfarin, so the instruction stands: tell your prescriber before starting AlphaCleanse.
The stronger reason for that instruction is milk thistle, covered on its own page.
Gallbladder. Ginger stimulates bile flow, so if you have gallstones or a bile duct obstruction, ask your doctor before taking AlphaCleanse.
Turmeric and dandelion root on the same panel do the same thing.
Pregnancy and breastfeeding. Ginger itself has a reasonable pregnancy record for nausea, but do not take AlphaCleanse if you are pregnant, breastfeeding or trying to conceive.
Other ingredients in the formula carry cautions that ginger does not.
Corroboration, not evidence of harm. Our registered study (NCT07738744) excluded 2 groups:
- People with severe digestive disorders including reflux, ulcers, IBS, IBD and a history of GI surgery.
- People on warfarin or antiplatelet therapy.
Those were design choices made before dosing. They tell you which groups were not studied, not that those groups were harmed.
Common questions
In short: take the capsules with food if they upset your stomach, and tell your prescriber before starting if you take warfarin.
Does 110 mg of ginger do anything, when the fatty liver trial used 2 g?
At 110 mg you are taking about an eighteenth of that trial dose, so no, we are not claiming the trial result.
The randomised pilot that people cite gave 44 adults with fatty liver 2 g of ginger a day for 12 weeks alongside diet and activity changes, and reported lower ALT, GGT and insulin resistance against placebo, with no change in AST (PMID 27110262).
AlphaCleanse contains 110 mg of ginger as 1 of 12 ingredients, and it is there for the digestive side of the formula rather than as a liver active.
Ginger's strongest human evidence is nausea, not liver enzymes, and a gram-level ginger dose is what a standalone ginger product is for.
AlphaCleanse is an anchor-and-support formula anchored by milk thistle at 165 mg, and the reason you can run this comparison at all is that all 12 amounts are printed on the panel, which is not true of the proprietary blends it sits beside.
Will it upset my stomach or give me heartburn?
It might, and ginger is the most likely reason if it does.
NCCIH lists abdominal discomfort, heartburn, diarrhoea and throat irritation as ginger's known side effects, and our own reviewers report a "harsh on my stomach" reaction often enough that we mention it before you buy rather than after.
2 things usually fix it: take the 2 capsules with food instead of on an empty stomach, and start with 1 capsule a day for the first week before going to the full serving.
Rhubarb root, also on the panel, is a mild laxative and accounts for the looser stools some people notice in week 1.
If discomfort persists past a fortnight, stop and email help@liverated.co. The 60-day money-back guarantee covers opened bottles, no questions asked, no restocking fee.
I take warfarin. Is ginger the problem?
Milk thistle is the bigger reason to check, not ginger, and you should still tell your prescriber before you start.
The warning about ginger and blood thinners comes from laboratory antiplatelet activity, and the best human test found none.
12 healthy men given a single 25 mg dose of warfarin, alone and after 7 days of ginger at recommended doses, showed no change in INR, platelet aggregation, warfarin clearance or CYP2C9 activity (PMID 15801937).
12 healthy young men is not a 60 year old on long-term anticoagulation, so treat that as reassuring rather than conclusive.
Milk thistle at 165 mg is the ingredient with a plausible CYP2C9 route, so the practical step is to tell your prescriber and ask for an INR check about 2 weeks after starting.
Does ginger help with bloating specifically?
The direct human evidence is for nausea rather than bloating, and we would rather say that than stretch it.
14 randomised trials in 1,506 surgical patients found ginger lowered postoperative nausea scores at 2, 6 and 12 hours, with no effect on vomiting incidence (PMID 34700257).
NCCIH's position is that ginger may help pregnancy-related nausea while motion sickness studies have mostly been negative. Bloating is measured less often and less well.
Our own 12-week study in 40 adults recorded a 38.6% fall in digestive symptom score, though it was single-arm with no placebo group and cannot separate ginger from the other 11 ingredients, so it is a whole-formula number rather than a ginger number.
If post-meal bloating is what brought you here, that whole-formula result and the 60-day money-back guarantee are the 2 things worth weighing, rather than the 110 mg of ginger on its own. No questions asked, no restocking fee.
The other 11 ingredients
AlphaCleanse contains ginger at 110 mg per serving.
See AlphaCleanse60-day money-back guarantee, no questions asked, no restocking fee.
Verified citations on this page: PMID 34700257, PMID 27110262, PMID 15801937, NIH LiverTox NBK600585, NCCIH ginger. Every PMID was confirmed to resolve to the paper named on 2026-09-09, and none was re-attributed in this pass.
Last reviewed: 2026-09-17